Electrochemical and Optical Analysis of Various Compositions of Au and Ag Layers for Blood Cancer Prognosis

The fabrication of silver (Ag) and gold (Au) thin film electrodes was successfully carried out using the DC sputtering deposition method. These were able to detect increase in serum albumin concentration that used as a prognostic factor for leukemia. simulation optical experimental analysis show an BSA can absorbance peak observed at wavelength 435 nm on hypoalbumin medium 470 normal medium. performance electrochemically tested, which it shown decrease oxidation reduction peaks occurred with respect concentration. An voltage 0.5 V Ag film. For Au, Au/Ag, Ag/Au films, 1.0 V. limits detection (LODs) Ag, Ag/Au, Au/Ag films 0.56, 0.24, 0.64, 0.36 g/dL, respectively. Therefore, based both electrochemical analysis, possessed highest potential prognosis monitoring leukemia compared other Au films.